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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCNA
All Species:
19.94
Human Site:
S261
Identified Species:
33.74
UniProt:
P12004
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12004
NP_002583.1
261
28769
S261
K
I
E
D
E
E
G
S
_
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534355
466
50130
S466
K
I
E
D
E
E
G
S
_
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P17918
261
28766
S261
K
I
E
D
E
E
A
S
_
_
_
_
_
_
_
Rat
Rattus norvegicus
P04961
261
28730
S261
K
I
E
D
E
E
G
S
_
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9DEA3
262
28869
G261
K
I
E
D
Q
Q
E
G
S
_
_
_
_
_
_
Frog
Xenopus laevis
P18248
261
28878
S261
K
I
E
D
E
E
A
S
_
_
_
_
_
_
_
Zebra Danio
Brachydanio rerio
Q9PTP1
260
28592
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17917
260
28812
Honey Bee
Apis mellifera
XP_001122985
261
29111
N261
K
I
D
D
D
E
E
N
_
_
_
_
_
_
_
Nematode Worm
Caenorhab. elegans
O02115
229
25366
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002313402
264
29135
E261
K
M
E
E
D
E
P
E
P
G
A
_
_
_
_
Maize
Zea mays
Q43266
263
29324
M261
K
I
E
D
D
E
E
M
K
P
_
_
_
_
_
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZW35
264
29204
T261
K
I
E
E
E
E
D
T
K
P
E
_
_
_
_
Baker's Yeast
Sacchar. cerevisiae
P15873
258
28898
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
55.7
N.A.
96.9
98.4
N.A.
N.A.
94.2
89.2
91.9
N.A.
70.5
62.4
40.2
N.A.
Protein Similarity:
100
N.A.
N.A.
55.7
N.A.
98.4
99.2
N.A.
N.A.
97.3
96.1
95.7
N.A.
85.8
81.9
62.8
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
87.5
100
N.A.
N.A.
44.4
87.5
0
N.A.
0
50
0
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
87.5
100
N.A.
N.A.
66.6
87.5
0
N.A.
0
87.5
0
N.A.
Percent
Protein Identity:
65.9
61.9
N.A.
64.7
35.2
N.A.
Protein Similarity:
84
82.5
N.A.
85.2
62.4
N.A.
P-Site Identity:
27.2
50
N.A.
45.4
0
N.A.
P-Site Similarity:
63.6
60
N.A.
63.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
58
22
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
65
15
43
65
22
8
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
22
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
65
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
72
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
8
15
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
36
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
43
50
58
72
72
72
72
% _